Texans vs. Colts prediction, odds, spread, injuries, trends for NFL Week 18

Sep 17, 2023; Houston, Texas, USA; Houston Texans quarterback C.J. Stroud (7) talks with
Sep 17, 2023; Houston, Texas, USA; Houston Texans quarterback C.J. Stroud (7) talks with / Troy Taormina-USA TODAY Sports
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The Indianapolis Colts and Houston Texans will face-off in a "win-and-in" scenario for both teams in the final week of the NFL season.

Few people expected either team to make the NFL postseason, but now one of them will secure a berth on Sunday. The winner of the game also has a shot at being crowned AFC South champs if the Jaguars fall to the Texans.

If you want to get my best bet for all 16 NFL Week 18 games, check out this week's edition of the "Road to 272 Bets".

In this article, I'm going to break down everything you need to know to bet on this AFC South showdown that has a playoff spot on the line.

If you want to bet on the Texans to get the job done, be sure to click the link below to sign up for an account at DraftKings Sportsbook. If you do, you'll receive $150 in bonus bets when you place your first $5 wager!

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Texans vs. Colts odds, spread, and total

Texans vs. Colts betting trends

  • The UNDER is 5-2 in the Texans' last seven games
  • Texans are 3-8 ATS in their last 11 games vs. Colts
  • Texans are 7-3 ATS in their last 10 road games
  • The UNDER is 8-3 in the Texans' last 11 games vs. AFC South opponents
  • The OVER is 5-1 in the Colts' last six games
  • The UNDER is 6-2 in the last eight meetings between these two teams
  • Colts are 6-13 ATS in their last 19 games vs. AFC South opponents

Texans vs. Colts injury reports

Houston Texans injury report

  • Sheldon Rankins - DT - Questionable
  • Will Anderson - DE - Questionable
  • Robert Woods - WR - Questionable
  • Noah Brown - WR - Questionable
  • Jonathan Greenard - DE - Questionable

Indianapolis Colts injury report

  • Kenny Moore - CB - Questionable
  • Braden Smith - OT - Questionable
  • Quenton Nelson - G - Questionable
  • Ryan Kelly - C - Questionable
  • Chris Lammons - CB - Questionable

Texans vs. Colts how to watch

  • Date: Saturday, January 6
  • Game Time: 8:15 pm EST
  • Venue: Lucas Oil Stadium
  • How to Watch (TV): ESPN/ABC/ESPN+
  • Houston Texans Record: 9-7
  • Indianapolis Colts Record: 9-7

Texans vs. Colts key players to watch

Houston Texans

Nico Collins: With Tank Dell sidelined, Nico Collins needs to help carry this offense as the clear No. 1 receiving options for the Texans. He has 1,102 yards this season but with no real No. 2 option, the bulk of the load will be on his shoulders in Week 18.

Indianapolis Colts

Gardner Minshew: Many Colts fans figured the team had no shot at the playoffs when Anthony Richardson suffered a season-ending injury, but Gardner Minshew has stepped in and taken this team to the doorsteps of the postseason. Can he take them one step further?

Texans vs. Colts prediction and pick

The winner of this matchup will clinch a playoff spot with a chance of winning the division and the loser will be eliminated. There's not much else you can ask for in a Week 18 showdown.

I think the Texans are the better team in this game. They're 11th in Net Yards per Play at +0.2 compared to the Colts at 17th at 0.0 and CJ Stroud didn't miss a beat in his return to the lineup last week.

The two defenses in this game have trended in opposite directions in the second half of the season. Since Week 10, the Texans' defense is 12th in opponent EPA per play and ninth in opponent success rate. The Colts are 19th and 21st in those two categories across that period.

I'll back the Texans in a near pick'em spot in Indianapolis.


Odds refresh periodically and are subject to change.

You can check out all of Iain's bets here!