Week 1 NFL Picks 2018: Can the Houston Texans earn the upset win?

HOUSTON, TX - OCTOBER 08: J.J. Watt #99 of the Houston Texans excites the crowd before the game against the Kansas City Chiefs at NRG Stadium on October 8, 2017 in Houston, Texas. (Photo by Tim Warner/Getty Images)
HOUSTON, TX - OCTOBER 08: J.J. Watt #99 of the Houston Texans excites the crowd before the game against the Kansas City Chiefs at NRG Stadium on October 8, 2017 in Houston, Texas. (Photo by Tim Warner/Getty Images) /
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INDIANAPOLIS, IN – AUGUST 25: Andrew Luck #12 of the Indianapolis Colts runs with the ball against the San Francisco 49ers in the first quarter of a preseason game at Lucas Oil Stadium on August 25, 2018 in Indianapolis, Indiana. (Photo by Joe Robbins/Getty Images)
INDIANAPOLIS, IN – AUGUST 25: Andrew Luck #12 of the Indianapolis Colts runs with the ball against the San Francisco 49ers in the first quarter of a preseason game at Lucas Oil Stadium on August 25, 2018 in Indianapolis, Indiana. (Photo by Joe Robbins/Getty Images) /

Thursday, Sept. 6

• Atlanta Falcons at Philadelphia Eagles (8:20 p.m. ET)

Game Preview: Not knowing how Nick Foles will play after a tough preseason makes this a tough game to choose. The Falcons eventually have to get over the hump and become the top team in the NFC, and that starts Thursday night.

Game Score Prediction: Falcons 21, Eagles 20

Sunday, Sept. 9

• Cincinnati Bengals at Indianapolis Colts (1 p.m. ET)

Game Preview: This will be a shootout between two teams, and fantasy football fans should really love this games as points will come to their teams in this game. Also, the return of Andrew Luck makes for exciting television.

Game Score Prediction: Colts 38, Bengals 31

• Buffalo Bills at Baltimore Ravens (1 p.m. ET)

Game Preview: Which will be more exciting this season, Bills Mafia pregame activities or seeing how long it takes the Buffalo coaching staff to replace Nathan Peterman with rookie Josh Allen? For Baltimore, this is a make-or-break year for Joe Flacco as Lamar Jackson is waiting in the wings.

Game Score Prediction: Ravens 17, Buffalo 7

• Tampa Bay Buccaneers at New Orleans Saints (1 p.m. ET)

Game Prediction: The Saints are favored to win the NFC South, and for good reason, as they have a Top 3 quarterback to make the rest of their offense play at a high level in Drew Brees. For the Buccaneers, not having Jameis Winston for the first three games will hurt the franchise and set them back to start the season with Ryan Fitzpatrick taking over under center.

Game Score Prediction: Saints 37, Buccaneers 10