DeAndre Hopkins, Garrett Graham questionable for Sunday

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Nov 17, 2013; Houston, TX, USA; Houston Texans tight end Garrett Graham (88) makes a reception during the fourth quarter as Oakland Raiders outside linebacker Kevin Burnett (94) defends at Reliant Stadium. The Raiders defeated the Texans 28-23. Mandatory Credit: Troy Taormina-USA TODAY Sports

Friday’s Houston Texans injury report saw two offensive starters in DeAndre Hopkins and Garrett Graham listed as questionable for Sunday’s road games in Indianapolis against the Colts.

Graham, the main option at tight end, will be a game-time decision with his hamstring injury, as he didn’t practice for the second consecutive day.

The tight end has 49 receptions this season with 545 yards and five touchdowns. He’s averaging 11.1 yards per reception.

Against the Jaguars, Graham had eight catches for 73 yards for a 9.1 ypc. He also had one touchdown in the loss. Graham has started in 11 games this season and played in all 13.

Hopkins is battling an ankle injury as he was limited in practice, Friday. Hopkins has 44 receptions this season for 707 yards and two touchdowns. he’s averaging 16.1 yards per reception.

Last week at Jacksonville, Hopkins tallied three receptions for 76 yards, with his longest reception going for 46 yards. He’s had multi-catch games the past two weeks, with two receptions against New England for 77 yards.

Losing Hopkins would be a huge blow for the Texans as their offensive already struggles as it is.

If the Texans (2-11) were to lose both Graham and Hopkins this week, it will be very hard for them overcome those odds and stop their 11-game losing streak.

Fifteen Texans players are listed as probable.

For the Colts, wide receiver Lavon Brazill is listed as questionable with a foot injury. He didn’t practice on Friday.

Listed as OUT for Sunday on the Colts’ roster are: fullback Stanley Havili (knee), defensive tackle Ricky Jean-Francois (foot), tackle Jeff Linkenbach (quad), center Samson Satele (elbow) and cornerback Greg Toler (groin).